I started watching this a few months back, but have just discovered it again: “Inbox Zero” Google Tech Talk at 43Folders.com.
Follows the Getting Things Done (GTD) / Take Back Your Life (TBYL) method, the video is just short of 60 minutes, but it’s great.
UPDATE: for some reason the short bit between the last two commas went missing when I published. Browser troubles, perhaps — I was using Opera. That will explain David’s comment below.